Curious as to your opinion. At what do you believe a HPTA restart is probably a waste of time to retain youthful levels, not just satisfactory barely above the normal levels. 35? 40? [/quote]
Depends in part on ones FT and TT levels relative to LH/FSH.
At the age ranges that you are considering, it is not a clear situation.
If the top end of the HPTA is stalled, one can try a restart.
Start with a SERM, not high dose, Nolvadex preferred by me, Clomid is OK if it does not drive you crazy.
Check LH/FSH, TT, FT and E2 after 4 weeks. If you feel a lot better, wait longer as thing are working.
If LH/FSH are still low, top end of HPTA is broken, stop and start T+AI+hCG.
If LH/FSH are good but T levels are poor, testes are not good enough, start T+AI+hCG.
LH/FSH and T levels are good, slowly taper off of SERM.
Use anastrozole throughout to keep E2 in lower 20’s and when tapering off of SERM, cruise on anastrozole at around 0.5mg/week.