Has anyone ever heard of or have any experience using this peptide as a potential means of maintaining some degree of testicular function, while on TRT? I find some of the research behind it interesting being someone who doesn’t tolerate hcg well, but also finds some benefit in hcg as well.
“Kisspeptin (aka metastin) is a naturally occurring protein in humans that plays important roles in during puberty & reproduction. It is also thought to alter mood & behavior, promote angiogenesis, and regulate kidney function. The peptide has also been found in the brain, and is known to suppress tumor growth and metastasis (spread). The peptide is of greatest scientific interest for its ability to influence gonadotropin releasing hormone (GnHR).”
Kiss-10 is the top of the reproductive cascade. The issue is it needs to be given every 2 hours via an insulin pump to mimic its natural pulsatile delivery. Dr. Seminara from MGH/Harvard has some fascinating literature studies on it.
