keto diet was the first diet i tried when I first started trying to lose weight. It worked really well for a while. Fast forward 8 years, I cannot get into ketosis anymore. I am currently on metformin which keeps my blood sugar level in the 80’s, but in its absence it is over 100.
i am just curious if this approach was a mistake in retrospect ( I am not trying to do a very low carb diet now - probably wont in the future either). Glucogenesis is inevitable from what I understand. So will very low carb diets always result in glucogenesis to the point where high levels of sugar are produced in the liver despite the diet - given enough time on the diet.
Once this cycle of glucogenesis starts, how do you improve insulin sensitivity to start repairing this mess? Seems like it would be impossible without the aid of a drug like metformin.
Your whole post was a little confusing, but I will try and decipher it. I am assuming you were talking about gluconeogenesis? Formation of glucose from other non-glucose counterparts (usually speaking of amino acids). I am sure a small amount of gluconeogenesis takes part in normal individuals on daily basis. The point you mentioned of it being absolutely inevitable though I am not sure is true.
As far as ketogenic diets increasing gluconeogenesis, perhaps temproraily until the body adapts to using ketones for energy sufficiently. Once your body is adapted to ketones as a primary fuel source, and assuming you are consuming adequate levels of dietary fats to fuel your body, there should be no increase in gluconeogenesis.
As pertaining to insulin sensitivity, being in a ketogenic state your body won’t be subjected to blood sugar and insulin swings, so the lack of contact from insulin to insulin receptors should actually increase insulin sensitivity in the long run.