Been busy with fertility research just recently, after our review appointment I was left with a lot of unanswered questions, unfortunately the clinics view is that we have been successful before so we should just keep trying the same thing, I on the other hand feel that something is missing and wanted to find answers. The get as many eggs as you can and then chuck my shit sperm at them and hope for the best approach may work again but l would rather try something new that may help.
My main question was if I’m a fit and healthy relatively young man, who doesn’t drink or smoke, eats a very healthy diet and has perfect blood results for sperm production, completely normal karotype, and the only problem is a blockage, then why would my sperm quality be so low that it’s affecting our embryo quality? The clinics answer was that surgical retrieved sperm never performs as well as ejaculated. I understand that but why?
One of the biggest factors in if a sperm can create a successful pregnancy is it’s level of dna fragmentation. All sperm has a small level of dna fragmentation but once it reaches a certain point it is not capable of creating a successful embryo. The fragmentation is caused by oxidative stress, this oxidative stress happens in the epididymis and is caused by defective or old sperm, there are levels of antioxidants in the epididymal fluid to help limit this damage. This normally only causes a small amount of fragmentation because the sperm do not stay in the epididymis for long. Unfortunately my poor little fuckers are stuck there! So it’s easy to assume that due to this they are subjected to higher levels of oxidative stress, research also finds that sperm quality declines gradually post vasectomy, I’ve had a vasectomy for 32 years!
Unfortunately there is no way of confirming my sperm fragmentation levels as the test requires higher numbers than what I have frozen and it also renders the sperm unusable. So although the test exists I can’t have it. So it’s just speculation that this is the problem.
There has been some studies that show that sperm dna fragmentation can be reduced and levels of epididymal antioxidants increased through supplemention. The clinic are open to trying this and have given there recommendations.
Ubiquinol q10 100mg
I have also added based on a study I found
Vit c 1000g
Vit e 500g
My wife has been recommended to take
Ubiquinol q10 100mg
I know full well that this may make zero difference but feeling like you are actively doing something really helps.
Sorry for the long non training related post, just getting out a few things that are on my mind.