It can be like a re-birth. Welcome back to the world you should have had.
The negative effects of AI are almost always from E2 getting low. Adjusting to get near E2=22pg/ml seems to work very well for almost all guys, some are simply wired differently. Non of the side effects that are published apply as they are from a target of E2=zero which is a very difficult situation for female breast cancer patients, who otherwise are going through a terrible experience.
When you take a steady dose of anastrozole, your serum levels of the drug take about 1 week to reach steady state. Do not make short term changes, results in a week. Full results may take 5-6 weeks in your case as there is a lot of E2 induced faulty wiring in your brain that needs new brain patterns.
Your mood and your relationships will improve greatly!
Most doctors are very poor at these things and your suffering is a measure of their incompetence and ignorance.
What you are doing does not line up well with the half-life effects of these drugs.
You are injecting 84mg T per week. 100mg seems to be better.
- self-inject 50mg T twice a week, subq not IM, #29 1/2" 0,5ml insulin syringe, pinch up fold of skin over upper leg, inject into end of fold with needle parallel to muscles below
- 0.5mg anastrozole at time of injections
- 250iu hCG subq EOD to preserve testes [and fertility]
A few guys, not rare, are anastrozole over-responders who crash E2, does not feel good, on standard doses. When that occurs, stop for 5-6 days and resume at 1/4th the expected dose.
Adjust anastrozole dose to get near E2=22pg/ml. If labs show E2=30, modify dose by a factor of 30/22. Similar if E2 is too low to reduce dose, result=x/target=22
Please read the stickies found here: https://forums.t-nation.com/t/about-the-t-replacement-category/38/2?u=ksman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body's temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.