As some of you know from the askphysiolojik thread I was experiencing extreme irritability for 4-5 days which then turned into pretty bad depression. Interestingly enough my libido has also been raging, quite a contradictory set of symptoms, horny and sad. I had labs done yesterday because something obviously wasn’t right. Here are the results:
Total Test: 658 Range 229-902
Free T: 21.6 Range 4.4-16.8 HIGH
E2 Sensitive: 45 Range 0-40 HIGH
SHBG: 12.5 Range 14.55-94.64 LOW
Compared to a month ago:
Total Test: 527 Range 229-902
Free T: 16.4 Range 4.4-16.8
E2 Sensitive: 25 Range 0-40
SHBG: 13.7 Range 14.55-94.64 LOW
Looks like my dose might be too high. I did lower it to 6mg today in order to bring down the E2. It also looks like my SHBG keeps dropping, is this to be expected? @charlie12 posted links to articles which stated that low shbg could be indicative of underlying issues. I am planning to make a PCP appointment to ask for A1C/insulin sensitivity to be done. I will have updated thyroid panels in one month as well.
Edit: Defy called me this morning. They’re pushing me to take the anastrozole to lower the E2 rather than manipulate my dose. They also said my Total T is lower than they’d like it and they’d actually like me to increase the dosage. I argued that Total T shouldn’t matter as much as Free T and that mine was high. They said my Free T is excellent, but that I was correct in saying that Free T matters more. Still, they’re pushing anastrozole and wanting me to add HCG as well to boost SHBG. I really don’t know what to do here. @physioLojik do you have any ideas on how I should proceed?