Guys, what’s everyone’s opinion on E2 levels being inconsequential to how operates when on TRT? A while back @NH_Watts posted a link to a discussion Jay Campbell had on his YouTube channel about the protective element of E2 and that numbers don’t matter as much as how you feel (this seems to be the general concensus rising in the community).
I guess my question would be: how does this apply across different SHBG levels and is SHBG a factor in how one feels at higher E2 levels? The reason I ask is that my E2 isn’t extraordinarily high at 45, but I’m symptomatic. Is this more a result of my T to E ratio rather than E2 itself? I want to increase my test dosage but not at the cost of my sanity if my E2 is just going to skyrocket due to my low SHBG.
What are your experiences with just letting E2 rise to where it may while on treatment?