Is my prolactin the issue

I have had libido issues on TRT. It’s been suggested that my E2 or my prolactin may be the issue. Keen to get opinions on my prolactin level and, if it’s an issue, how to get it into a more favourable range

140mg / week injected daily - 500iu HCG

SHBG - 15 (18.3 - 54.1) nmol/L

OESTRADIOL 62 (41 - 159 R) pmol/L

TESTOSTERONE 23.3 (8.64 - 29 R) nmol/L

FREE TESTOSTERONE -0.69 (0.2 - 0.62 R) nmol/L

FREE ANDROGEN INDEX 150.3 (24 - 104 R)

PROLACTIN 253 (86 - 324) mU/L

TSH 0.847 (0.27 - 4.2)

FREE T3 5.34 (3.1 - 6.8)


You do not have a prolactin issue. You do have low E2 issue, as your ratio of testosterone to estrogen is too high.

You need a higher dosage of hCG, estrogen therapy, or DHEA which will convert to estrogen in men.

Anything <83 pmol/L or 20 pg/mL is considered low in adult males, children typically score at the bottom end of those ranges.

Estrogen, the main sex hormone in women, and plays a bigger role in male libido than previously thought, according to research that may guide development of sex-drive treatments.

The study found that reducing estrogen in men undergoing treatment for low testosterone resulted in a drop in libido and an increase in body fat, even as testosterone levels improved.

The research is published in the New England Journal of Medicine.

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Is it confirmed DHEA converts to E2 in men? I can try that.