Introduction - 34 Y/O with CAH Starting TRT

Have you tested:
A1C?
TSH
fT3
fT4

Please see last paragraph to eval thyroid function. This can have a big effect on fat gain/loss.

Loss of 15 pounds in a month is getting dangerous. This can damage your adrenals - my attempt as a joke. Fat fat loss also liberates a store of fat soluble hormones, toxins and drugs.

With TRT please watch these carefully: HTC [hematocrit], RBC, hemoglobin and ferritin. Concerned with high HTC. If a problem, you need to avoid iron fortified flour, cereals, breads, rice and vitamins listing iron.

T peaks are thought to make RBC worse and 200mg was bogus.
You need steady T levels, avoiding peaks. subq is smoother than IM.

  • Self inject 50mg T twice a week, subq, #29 1/2" 0.5ml insulin syringe. Do not inject IM. Pinch up skin over upper leg, inject into end of fold with needle parallel to muscle layers. Slow to load, injection times are OK, but not fast like Docs and RNs expect. After injecting, press finger on injection site for 10-15 seconds and the compression will prevent bruise bleeds by allowing tissues to seal off.

  • 0.5mg anastrozole at time of injections to mange E2 near E2=22pg/ml

  • 250iu hCG subq EOD to preserver testes and fertility. Expect small testes otherwise and loss of other testicular hormones. Some wives object to tiny testes

Prolactin needs to be tracked. Can be from a prolactin secreting pituitary adinoma. If there is gets large, can press on optic nerves. Easily managed with oral 0.5mg Dostinex/cabergoline per week. Can be confirmed via MRI.

Do not understand why LH/FSH not tested.
Too late now as both -->zero on TRT.

E2 estradiol should have been tested.

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.