Background: I am using 99% pure dbol powder purchased directly from a Chinese chemical company at a low 7mg dose once in the early AM - around 8:30am - 9:30am as HRT since my Testosterone is half normal (I'm 35 and was tested three weeks ago at 340 ng/dl when my level should be around 650 ng/dl). At the three-week mark - dosing started August 7th, 2013 - Dbol alone has successfully reversed all the nasty physical and mental effects of low Testosterone. Symptoms which have been building for close to two decades. For a detailed explanation see the thread here:
Low Testosterone, Still in Range
First, the reasons I tried this route of administration this morning:
Speed. In order to minimize the suppression of my remaining natural Testosterone production, I take a single small dose of 7mg measured on an accurate 1mg digital scale each morning. However, I have to hurry each morning to get the dose in so it overlaps with my natural Testosterone spike to minimize suppression. So far this is working well but I choose not to eat any food for the first two hours to speed absorption. This means low blood sugar and symptoms since my body is so lean that I have no reserves. The idea behind insufflation is that direct absorption through the nasal and sinus mucosa should be far faster than slow digestion. Normally the strong physical effects from ingestion manifest in one hour - body warmth, sweaty palms and strong physical energy.
Hepatotoxicity Reduction. Ingestion results in a bit of liver damage as the molecule is absorbed into the portal circulation and undergoes first-pass hepatic metabolism before it can enter the bloodstream. Direct absorption into the bloodstream bypasses first-pass metabolism - at least with the tiny 7mg dose split in half between nostrils, the amount is so tiny that the mucosa absorb at least 80% with the rest dripping down into the stomach. This decreases liver damage significantly.
Needle not required. I hate needles and will never use them. Injection is physically damaging to the body, painful, and brings the daily risk of infection, sterile abscess and the illegal possession of a hypodermic needle. All things I won't tolerate. Insufflation delivers molecules with a speed and absorption efficiency which can only be beat by two other methods: injection and inhalation - vaporization or smoking.
Different effects. The possibility that negative effects might be minimized and positive effects maximized due to different absorption and conversion. Intestinal cells have a high expression of the Aromatase enzyme and so ingestion results in a very different physical and psychoactive effects than direct methods such as injection.
This morning at about 9:36am I scaled out the usual three microscoops [eBay sale & pic for scoop size reference: http://www.ebay.com/itm/171054265557 until my scale - the Horizon PRO-20B: http://www.ebay.com/itm/220862213004 - read 7mg into the tiny polymer shot-glass I've been using these past three weeks.
This time was different because I had my trusty plastic straw dug up from the basement storage.
With a bit of trepidation and worry about pain, I carefully insufflated half the dbol up one nostril and half up the other at exactly 9:41am.
The feeling of this pure powder up the nose is nothing at all. Absolutely nothing. Like breathing air. There is no feeling of pain, no burning at all. I could not tell that I had taken anything. After five minutes a very slight just barely noticeable taste of the usual Aspirin-like flavor but smelled inside the nose instead of tasted on the tongue. Nothing annoying or distracting at all.
At 9:51am - only ten minutes later - I noted a distinct and strong psychoactive effect: a fast mental clarity and sharpness which I had normally observed about an hour after ingestion these last three weeks of oral dosing. I must emphasize: FAST, very very quickly and very very clearly.
Strangely, the very mild positive almost euphoric feeling that occurs about an hour after oral ingestion did not occur. Instead, after another twenty minutes of what I presume was further absorption I felt the strangest mental effect of all the psychoactive substances I've ever tried. My historical experiences with psychoactives include DXM, LSD, MXE, Cannabis, 5F-AKB48, 5F-PB22, Nicotine, Piracetam, Pramiracetam, Oxiracetam, Aniracetam, Noopept, Morphine (once in hospital), Codeine (six oral doses in hospital after appendectomy surgery a few years ago), an unknown Benzoziazepine (a single dose in hospital pre-surgery), Sunifiram and Nefiracetam.
This effect was mild but totally unique. It's so unique that it must be experienced. It came with a tiny bit of dizziness and a strong buzzy feeling in my legs.
Between this time and the time when main effects started I noticed another distinct and exaggerated psychoactive effect - one far stronger but similar to the effects I have noticed after ingestion: a strong and total mental 'silence' of thought combined with a strong visual sharpness and clarity.
The main body effects still took one hour to manifest - the warm sweaty palms, internal furnace-like heat and physical energy along with the usual very, very mild positive mental effects.
The most amazing thing is that after one hour these main effects manifested - and increased in intensity - until peaking at the two-hour mark with at least 50% more power than normal. Insufflation increases absorption by 50% compared to oral dosing. The usual 7mg - three microscoops - is now an overdose! Since my scale won't read less than that I will be taking only one unmeasured microscoop instead of the usual three - about 2.5mg - 3.0mg (!) each morning for the next week to get a more complete picture of the effects.
That's the plan for the next week of insufflation testing because I now see that this method - used only for the tiny morning dose as HRT - is far, far superior to ingestion by preventing both first-pass metabolic losses and a good portion of liver damage caused by portal absorption and first-pass metabolism - killing two birds with one stone
Here's the differences from oral ingestion in short form:
- Fast strong psychoactive effects that begin in ten minutes but are uniquely different from oral dosing.
- Less hepatotoxicty due to bypass of first-pass metabolism.
- Far higher potency with about 50% increase in activity for the same dose in mg.
- Food can be ingested without slowing absorption so I won't need to deal with two hours of morning fasting and low blood sugar.
I recommend anyone with pure powder to try insufflation at least once. It's painless and safe. However, if the goal is to maintain a steady blood concentration or larger amounts are used (higher insufflated doses will result in more spillover into the stomach due to sinus drip, negating the benefits of insufflation) then this method is not recommended. My routine is a single morning microdose to produce a spike which overlaps the morning Testosterone release so it's perfect.