here are a couple threads with some good info
Here is a clip from one of Cy's articles
Zit Zapping Drugs
Q: What's the latest in acne treatments? I tried Accutane years ago but the side effects were too much for me.
A: A current theory for acne pathogenesis involves four main factors: an abnormal increase in sebum production; follicular keratinization (followed by microcomedone formation); proliferation of bacteria; and inflammation/delayed-type immune response.
With that in mind, the only two treatment options that hit all four causes are isotretinoin (Accutane) taken orally and hormonal therapy/oral contraceptives. If you're male, "the pill" is out of the question.
In any event, Accutane is really a bit much unless you have severe acne. For most guys, topical antibacterial treatments like azelaic acid and benzoyl peroxide are sufficient. Both seem to address two or three of the proposed causes of acne.
Other than that, a rather new topical drug, adapalene (Differin), addresses three out of four of those causes. Tazarotene (Tazorac) is worth giving a try as well.
My main point is that most guys will do just fine with benzoyl peroxide, so be sure to start with the least effective compounds, so to speak, before deciding to give more effective and perhaps toxic compounds a try. (14)