Inflammation control is always a big topic around here and I just happened read an article today addressing just that subject. I searched here for the herbs mentioned and most have only been lightly touched on in that respect.
Heres a very brief overview, perhaps some of the T-staff can elaborate.
The compnenets tetrandrine (Tet) and fangchinoline (Fang) have been shown to suppress multiple inflammatory cytokines and mediators.
Acetyl-II-keto-beta-boswellic acid, (AKBA) is a selective inhibitor of 5-lipoxygenase (5-Lox). 5-Lox converts arachidonic acid to the highly inflammatory leukotrienes.
Luteolin is among the most potent and efficacious flavonoid inhibitors of LPS [germ cell wall fragment]-induced TNF-[alpha], interleukin-6 production and inducible nitric oxide expression.
Stinging Nettle Leaf:
Nettle leaf extract (NLE) has been shown to reduce IL-2 and interferon-gamma release by monocytes. NLE was shown to reduce secretion of TNF-alpha by human dendritic cells, leading to reduced T cell-mediated inflammatory response.
Holy basil leaf extract (HBE) has been reported to be an inhibitor of both cyclooxygenase-2 (COX-2) and 5-lipoxygenase.
Green Tea Polyphenols:
EGCG and green tea extract (GTE) inhibited neutrophil-mediated angiogenesis in an in vivo inflammatory angiogenesis model.
EGCG reduced expression and activity of COX-2 in human chondrocytes (cartilage-producing cells) from osteoarthritis cartilage and GTE reduced inflammatory PGE2 production when the chondrocytes were stimulated with IL-1 beta.
EGCG was found to inhibit COX-2 without inhibiting COX-1 expression.
The USDA Phytochemical Database reported as of 1999 that ginger has more 5-lipoxygenase inhibitors than any other botanical source.
by James South, M.A.