Please don't take offense to what I am gonna say, but I would like to her people thoughts.
The indigo supplement that T-Nation has brought out is amazing bit of kit, no dought! But what I have notice is that tho people are getting results from it are they using it in the right way.
what I am trying to say is would it be better for the overweight person to lose as much weight as they can naturally without the sup, and the start the supp when they are down to a decent % bf. Surely this would be more beneficial than taking it until u reach the goal that you want?
which brings me to my second question, surely if you take indigo for a long period of time your body will become custom to it effects and start to build a resistance to the effects? I mean if you look at other thing like, caffeine, creatine, and even whey to an extent, you body builds some resistance to the supplement and you don't get the same effect as you once did.