On certain exercises they may cause a minor decrease in performance. The dead lift being a good example here... But by wearing gloves and/or straps on most other exercises you simply wont have the calluses to rip off come time to dead lift I have found.
There is no trophy for having the biggest callus torn from your palm, trust me I looked. If there is an issue that is causing problems in your lifting (or your life, as the case may be here with skin ripping off your hand) and there is an easy solution, I say go for it.
I understand the mind set that would not allow one to use gloves (I can hardly believe it myself but I used to live it, the whole macho tough guy bullshit attitude. Not saying this is you, but many who don't wear gloves are of the "gloves are for pussies" mind set) but I now understand the mind set that allows one TO use them, because that is my life now... My lifting hasn't gotten worse because of it, and my life is a teeny tiny but easier.