I have two sets of IGF-1 lab results from two different doses.
First GH=0.9iu/day sc, IGF-1=204
Second GH=1.34iu/day sc, IGF-1=332 (GH dose is 57 % increased)
If you plot these two results you get a straight line that also intersects (0,0).
The IGF-1 dose response is linear. So one can get the slope of the line with only one data point, the first or latest lab result. In my case, the slope IGF-1:iu/day is 332/1.43=232.17. With this number, one can calculate what GH dose is required to achieve a given IGF-1 target. For me, a dose to achieve IGF-1=300 would be 300/232.17=1.292
Or if one wants to get to new dose, new_dose = old_dose *(target IGF-1 / current IGF-1)
IGF-1:iu/day GH will vary by ones weight [perhaps] but is mostly controlled by one’s liver. And obviously, the potency of the GH is a major factor.
My AM cortisol improved/increased, now 19.3 [4-22]. Suspect that GH increased that.
Before starting rhGH my IGF-1 was 89.
Why 1.43 iu/day? Doc wanted 1.5iu/day. I can get 7 doses of 1.43iu out of a 10iu vial. If I took 1.5iu/day I would be near IGF-1=350 ng.ml
My analysis also indicated that my endogenous GH production was around 0.4iu/day. And the first 0.4iu of my dose simply replaces what I was making and is a benefit loss. Those most in need get the best cost benefit.