Can anyone comment on whether there are connections between IGF-1 levels and use of exemestane/Aromasin? I’ve seen conflicting reports on the way that different AIs affect IGF-1, and I’m especially curious if anyone can share both anecdotal and research-based info on how Aromasin may affect IGF-1. The conflicting reports are that many forum posts say that exemestane raises IGF-1, while others have said that it lowers it. To confound things, on another forum I’ve seen comments that Arimidex lowers IGF-1 while Aromasin raises it. I’d be grateful for any feedback, guidance, etc.