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Ibuprofen Hinders Muscle Growth

Inhibition of the cyclooxygenase-2 enzyme : with anti-inflammatory drugs like ibuprofen, acetaminophen, or aspirin, prevents the
formation of active prostaglandins. The anabolic
cascade is stalled without sufficient
prostaglandin formation interfering with
the normal increase in protein synthesis rates
after exercise. It is often advised to use such
drugs only when necessary if muscle growth is a
key focus.

(Am J Physiol 'Endocrinol Metab 282:E551-6)
Anabolics 2009, Llewellyn

Damn, guess we’l just have to use opiods instead :slight_smile:

who cares… just lift and you posted this in the steroid section.

if your on steroids who fuckin cares your building muscle more than us naturals anyways so stop giving a fuck.

its like when people think they are overtraining. and worrying about drinking enough water, fuck…

“the kitchen doesn’t make you big, the weights at the gym do”

[quote]Joelsopher wrote:
“the kitchen doesn’t make you big, the weights at the gym do”[/quote]

I disagree. The motto I like is:

Lift Big, eat big, sleep big, get big.

It’s all of those things combined that builds muscle. Proper training, proper nutrition, and proper rest.

Oh, and gear helps too (but it’s not a replacement for any of the previously mentioned).

[quote]gallegom wrote:

(Am J Physiol 'Endocrinol Metab 282:E551-6)
Anabolics 2009, Llewellyn[/quote]

So is this an actual study? Or a reference by some steroid guru?

[quote]Joelsopher wrote:
who cares… just lift and you posted this in the steroid section.

if your on steroids who fuckin cares your building muscle more than us naturals anyways so stop giving a fuck.

its like when people think they are overtraining. and worrying about drinking enough water, fuck…

“the kitchen doesn’t make you big, the weights at the gym do”[/quote]

Lol, its actually the opposite. Lifting weights is the easy part. Enough enough food to grow is the part most people suck at.

[quote]Detroitlionsbaby wrote:
gallegom wrote:

(Am J Physiol 'Endocrinol Metab 282:E551-6)
Anabolics 2009, Llewellyn

So is this an actual study? Or a reference by some steroid guru?[/quote]

This post was flagged by the community and is temporarily hidden.

As far as actual study of ibuprofen, this is TRUE all nsaids cause muscle hindrance. Its been studied alot. I will try to pull some actual med reports from school. but i think OP sited that tylenol (acetaminophen)and aspirin will also hinder muscle growth. That is not in any study im aware of.Edit* Acetaminophen is not nsaid, (aspirin is) and it has been found that nsaids cause loss of muscle producton and in some cases of high dosage actual muscle reduction.

[quote]albig wrote:
As far as actual study of ibuprofen, this is TRUE all nsaids cause muscle hindrance. Its been studied alot. I will try to pull some actual med reports from school. but i think OP sited that tylenol (acetaminophen)and aspirin will also hinder muscle growth. That is not in any study im aware of. Aspirin and Tylenol are not nsaids, and it has only been found that nsaids cause loss of muscle production and in some cases of high dosage actual muscle reduction.[/quote]

Aspirin is an NSAID.

[quote]albig wrote:
Aspirin and Tylenol are not nsaids, and it has only been found that nsaids cause loss of muscle production and in some cases of high dosage actual muscle reduction.[/quote]

Aspirin is definitely an NSAID. Tylenol (acetominophen) is not.

[quote]BL4DE wrote:
Joelsopher wrote:
“the kitchen doesn’t make you big, the weights at the gym do”

I disagree. The motto I like is:

Lift Big, eat big, sleep big, get big.

It’s all of those things combined that builds muscle. Proper training, proper nutrition, and proper rest.

Oh, and gear helps too (but it’s not a replacement for any of the previously mentioned).

[/quote]

Dont forget poop big :stuck_out_tongue:

Edited and thank you wasnt paying good attention to my post and you are very much correct about aspirin.

The real world seems to disagree. Lots of guys use lots of pain relievers and are big.

[quote]Pretzel Logic wrote:
The real world seems to disagree. Lots of guys use lots of pain relievers and are big. [/quote]

Definitely. I think it’s just one, relatively small factor. No reason to blow things out of perspective.