You need to look at other parameters which is the job of a trained health professional to do. When dealing with these cases one needs to look at a lot of variables in order to determine what direction one should go with in order to give the best clinical approach. I have been consulting with medical professionals for 4 years.
Before one can even look at what protocol to follow, a full medical history as well as events leading up to how they are feeling are needed. Correcting adrenal and thyroid has in my experience help to regulate T production avoiding people from going on HRT. Again one needs to look at biological, emotional, mental,environmental stress in a person to know what came first.
I tend to have medical professionals treat the adrenals and thyroid first along with lifestyles, nutrition, and sleep hygiene before moving on to HRT if its really necceary.