Cholesterol: Better near 180, <160 known association with increased all-cause mortality. Are you using a statin drug? That can have negative effects for some people.
“Estradiol 49 too high (even taking Adex .25 -.5 / week)”
You need to be on a steady dose for some time for the labs to be useful. .25 - .5 is not good enough. If you feel that you know the Adex dose that was used for 7-14 days prior to the labs, increase by a factor of 49/22 where the goal is 22pg/ml.
Are you now taking DHEA? A few guys freely convert DHEA–>E2 in their adrenals.
Many cases of thyroid autoimmune disease are thought to be caused by elevated TSH, often from low iodine AND selenium deficiency.
The process that makes T4 produces free radicals that an enzyme normally clean up. But that enzyme must have selenium as part of its structure. If the free radicals are not cleaned up, cell damage occurs and the immune system cleans up the wreckage. Then the immune process can mistake normal thyroid tissue as foreign and you are auto-immune. There are cases of Hashimoto’s resolving with ample selenium and ample iodine.
Find high potency B-complex multi-vits that list 150mcg iodine AND 200mcg selenium, as well as other trace elements.
TSH should be closer to 1.0, you can’t go by the ranges, those are ridiculous. fT3 and fT4 should be mid-range or a bit higher.
Thyroid function is a rather complicated thing. But easy to access by checking oral body temperatures. Please see last paragraph in this post.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- HPTA restart <<<<<<<<<<<<<<<<<<<<<<<<
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.