I just discovered a link from another thread that leads to a study that answers my question with very encouraging results, indeed!
Here’s the link:
The name of the study is:
Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testosterone Levels
Here’s the study group and what they were given:
“We investigated the ability of the orally administered aromatase inhibitor, anastrozole, to increase endogenous testosterone production in 37 elderly men (aged 62 to 74 yrs) with screening serum testosterone levels less than 350 ng/dl. Subjects were randomized in a double-blind fashion to the following 12-wk oral regimens: group 1: anastrozole 1 mg daily (n = 12); group 2: anastrozole 1 mg twice weekly (n = 11); and group 3: placebo daily (n = 14).”
The results were nothing short of amazing:
“Mean SD bioavailable testosterone increased from 99 + or - 31 to 207 + or - 65 ng/dl in group 1 and from 115 + or - 37 to 178 + or - 55 ng/dl in group 2”
“Total testosterone levels increased from 343 + or - 61 to 572 + or - 139 ng/dl in group 1 and from 397 + or - 106 to 520 + or - 91 ng/dl in group 2”
“Serum estradiol levels decreased from 26 + or - 8 to 17 + or - 6 pg/ml in group 1 and from 27 + or - 8 to 17 + or - 5 pg/ml in group 2”
“These data demonstrate that aromatase inhibition increases serum bioavailable and total testosterone levels to the youthful normal range in older men with mild hypogonadism. Serum estradiol levels decrease modestly but remain within the normal male range.”
Clearly, anastrozole alone is a viable alternative to TRT for men who do not have access to conventional TRT therapy. I would have thought that 1mg/day was an excessive dosage, but this study would seem to indicate that it is not. I wouldn’t start that high, but it certainly gives me a new picture of the landscape, so to speak.
Thanks to mikandrea for the original link!