From the MPMD website (I can’t find the actual study, but I did read it).
In the study using young men with GH / IGF-1 deficiency, doses of 10 and 15 mg per day were used, and the results were pretty good IMO. Results below:
"In a study conducted on nine severely GH-deficient men ages 17-34 yr, 10 mg MK-677 increased serum IGF-1 levels by 52% on average, and increased GH levels by 79% on average.
50 mg MK-677 increased serum IGF-1 levels by 79% on average, and increased GH levels by 82% on average [R].
Placebo Vs 10 mg MK-677 Vs 50 mg MK-677 in GH deficient men – GH Levels
Placebo Vs 10 mg MK-677 Vs 50 mg MK-677 in GH deficient men – IGF-1 Levels"
Now I have low IGF-1 on blood tests (about 120). I am very similar to the participatents in this study. If I can get an 50% improvement in IGF-1 and close to 80% improvement on HGH for $0.50/day, that is a win. I still need to do blood work to confirm it is working. If not, I’ll probably go to HGH injections.
I think a good conclusion from this is that using more doesn’t equal a lot better results, and 50 mg is 5X the 10 mg dose (that was almost as effective). Using 10 mg is not going to spike hunger as much, and is a fifth the cost.