I will stick to the question in general. Things specific to your case should be kept in one of your other threads so you are not spread out so much that context is lost.
Anastrozole is competitive to T. Injecting T once a week leads to large changes in serum FT [or bio-T], so FT-->E2 production rates are changing. If FT is changing and serum levels of anastrozole are not, dose will not be optimal.
Inject T twice a week and take anastrozole at that time. Then FT and anastrozole levels will roughly rise and fall together. Consider subq T injections for smoother levels with #29 1/2" 0.5ml insulin syringes.
You may need to switch to an anastrozole solution, 1mg/ml in vodka, to allow for arbitrary dosing amounts to get near E2=22pg/ml - 80 pmol/L