I know I have hit my sweet spot several times in the ast on androgen. Problem is, I don't stay there very long
Last year I began androgen with my family doc who knew nothing about TRT sadly. He only checked total T.
I remember when my total T was 750 I felt so good, for only a few weeks though. Now I was at 1050 and feel like crap, but my E2 was 95. I don't know what my E2 was last year with the other doc.
I will say though, every single time we increase my dosage, I feel really good with libido and all the rest, but it only lasts a couple of weeks. I feel like a junkie chasing a high that I can't catch