Been trying to make TRT work for me for just over 2 years, really only having success with it at the start. Tried numerous protocols, dosages, as well as HCG for a couple months and just can’t seem to get it to work. Lately been feeling like shit mentally, anxiety/worry and a bit of depression now which is highly unusual for me. Feel like a menopausal woman. Also sleep like shit.
Working with a TRT NP who isn’t big on dosages over 100mg per week, which is fine as I’ve had sexual sides above that I don’t like. My current protocol is the result of trying to find the balance between effectiveness and a shitload of sides I seem prone to based on dosage (all manner of sexual sides, acne, thinning hair, sweating, sleep problems, mental issues)
Drawn in trough AM
Current protocol 70mg Enanthate IM once per week (been 9 weeks at this protocol)
CBC & Lipids all normal unchanged
Dehydroepiandrosterone [DHEA-S] = 9.1 <15.0 umol/L
Thyroid Stimulating Hormone [TSH] = 0.62 0.32-4.00 mIU/L
Thyroxine Free [Free T4] = 12 9-19 pmol/L
Estradiol = <40 <162 pmol/L (under 0-10 pg/ml)
Testosterone Total= 13.3 8.4 - 28.8 nmol/L (383.3 ng/dl)
Testosterone Free = 350 196-636 pmol/L (101 pg/ml)
The biggest difference in values that I can see is my current E2 is way lower than it used to be. When I felt TRT was working well for me, it was consistently over 100, yet now is low enough to not be able to measure accurately at the same protocol 12 months later. I have never taken AI’s, just HCG approximately 12 months ago and a bunch of protocol changes trying to dial it in.
Anyway, something with this is making me feel worse on it than off and just looking for help.
Also, I live in Canada, which has pretty shitty healthcare lately, so these are the only test results I have besides PSA.