Is the issue testicular maintenance or fertility? Would be useful to know your TRT protocols and other things.
HMG is extracted from the urine of menopausal women, who are producing high amounts of gonadotropins trying to get estrogens from failing ovaries. It does not contain LH and FSH only. hCG may be a minor component.
You are correct that the LH in hMG can do everything that you need. Using less with hCG might have some cost advantages if the outcome is otherwise favorable.
High amounts of LH receptor activation in the testes may lead to high E2 levels, that anastrozole may not be able deal with effectively. High amounts of LH can do the same thing as hCG. [I have no idea from this post what your E2 issues with hCG were.] When normal males take 1mg anastrozole per day, LH levels increase a lot and E2 levels rise, because anastrozole cannot modulate T–>E2 inside the testes. That demonstrates that LH can lead to the same E2 issues as hCG.
I have no idea what the dose of HMG would be to replace 250iu hCG EOD. You will be better off injecting HMG every day, or perhaps twice per day. LH has a short half life.
more HMG info:
“”“Repronex is a fertility medication that is injected either subcutaneously or intramuscularly. It contains follicle stimulating hormone and luteinizing hormone purified from the urine of postmenopausal women.”"" Does not state that there is no hCG. In any case, the LH and whatever amount of hCG there is will be doing the same thing.
More: ““RepronexÂ® (menotropins for injection, USP) is a purified preparation of gonadotropins extracted from the urine of postmenopausal women. Each vial of RepronexÂ® contains 75 International Units (IU) or 150 IU of follicle-stimulating hormone (FSH) activity and 75 IU or 150 IU of luteinizing hormone (LH) activity, respectively, plus 20 mg lactose monohydrate in a sterile, lyophilized form. The final product may contain sodium phosphate buffer (sodium phosphate tribasic and phosphoric acid). RepronexÂ® is administered by subcutaneous or intramuscular injection. Human Chorionic Gonadotropin (hCG), a naturally occurring hormone in post-menopausal urine, is detected in RepronexÂ®.””"