Old thread here:
Anastrozole is competitive with T at aromatase enzyme reaction sites. Serum anastrozole levels need to match serum T levels. With pellets, T levels change over time and you cannot get E2 levels under control.
Anastrozole needs to be dosed at least twice a week.
With those T levels you might have needed 1.5-2mg anastrozole per week at that time.
You now see how important E2 management is and how difficult pellets are.
FT determines FT-->E2 production rates. Liver clears estrogens. Liver function is important and AST/ALT labs are useful. Some meds or conditions interfere with liver E2 clearance.
You will be better of self-injecting T subq twice a week and taking anastrozole at time of injections.