Considering fructose’s potent reduction of SHBG, and insulin as well, I think it’s interesting that no one ever told you to EAT MORE CARBS (as in, fruits primarily)
Oh, and proteins, too.
I’m the same low e2, low free T %, high SHBG type of guy. I wasn’t eating enough, I was training hard, there’s no mystery. At the time, just like your docs, I thought that the solution was TRT, and I eventually came off when I realized how bad my self diagnosis was (those were good years on the juice though). TRT won’t do shit to lower SHBG. It will improve your free T levels though, obviously.
Now that I’m still using SERMs on and off, I get a slow raise in hormones… and the side effects you describe when I’m on the SERMs. It’s crystal clear that your problem is either lifestyle or diet. Because that’s always pretty much the same story.
I’m a pharmacist, and no pharmaceuticals will fix a metabolic disorder.
Insulin regulates testosterone and sex hormone-binding globulin concentrations in adult normal weight and obese men. (R Pasquali and al.)
Abstract : There are no studies in vivo on the effects of insulin on androgens and sex hormone-binding globulin (SHBG) in men. We, therefore, investigated the effects of insulin suppression on testosterone and SHBG in two groups of eight nondiabetic adult obese men and six healthy normal weight men who underwent diazoxide treatment (100 mg, three times daily) for 7 days. […] In conclusion, these results indicate that in vivo, insulin is capable of stimulating testosterone production and, simultaneously, of inhibiting SHBG concentrations in both normal weight and obese men.
your high urinary cortisol also indicates that you’re not eating enough carbs IMO. Could be Gluconeogenesis 101 right before your very eyes. And the best way to stop GNG would be more Glycogenolysis = more liver glycogen = more fruits. Circling around