Does High Hematocrit Lead to Complications for Men on TRT?

[readalot]

Can you minimize Hct increase through modulating your dosing frequency?

What Benefits with Different Injection Frequencies?

I’ll posit this has to do with both dose and frequency. If I remember correctly trying to trace back the kinetics of testosterone on hepcidin suppression and to EPO, it’s first order. Once you reach saturation, you can’t make more RBCs. If your dosages are too high then daily frequency ain’t going to help if you are sensitive. Here’s an example (me at 140 mg/week of TC - 98 mg/week of testosterone): [image] Doing once weekly brings me back into physiologic range a good portion of the PK pr…