CT I will keep it short. With programs such as Best Damn Natty and other high frequency routines, the primary argument I have heard against them is that although the individual muscles have days off (example push muscles M-W-F, pull T-TH-SA) you are taxing the same CNS everyday Mon-Sat. Some trainers have stated that training till failure, training with a high % of your 1RM, set extenders and focusing on the negative reps are very taxing in the CNS. I assume the low volume in each session would be a mitigating factor. Can you please share your thoughts.