Your TT was high. But that can be from high SHBG creating a lot of [non bioavailable] SHBG+T that inflates TT, then TT overstates your T status.
SHBG is made in the liver to scavenge sex hormones from the blood. SHBG increases with [your] high E2, more FT or bio-T lowers SHBG. SHBG reduces FT as in increases TT.
E2=22pg/ml is a target that works well for almost all guys. Increase dose of aromasin by factor of 50/22. You might find ~1.0mg/week anastrozole is more cost effective.
E2=75 is clearly VERY abnormal for your T dose. This may be indicating poor E2 clearance rates by your liver. AST/ALT lab results need to be available. Liver conditions/disease can do this too. Some medications, Rx and OTC can cause this by competing for the same enzyme pathways that metabolize estrogens.
Please post all of your lab work, in list format with lab ranges. Not just what you think is important.
Labs:
TT
FT
E2
…
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.