A few women have come here via google and I have assisted.
I have helped a few women in real life. One gal here was long term for her then her hubby.
Women start to have progesterone decline in their 30's, similar to how women and men have DHEA decline. Progesterone balances estrogens. As progesterone drops, women become estrogen dominant, leading to painful periods, breast tenderness and over stimulation, thickening of endometrium, heavy periods, PMS, fibroids ... I believe that most women ?all? should be using progesterone cream at some point to manage these effects and progression and that a large number of female cancers could be avoided.
Men can be guided well with lab work. Women have hormone changes by the day and there is a vast difference across women. So nothing is standard and women on HRT really need to read their condition to determine HRT dosing which needs to change during her cycle. Things can become uncontrollable in perimenopause and that can lead to a need for ablation or resection of the endometrium as blood loss can lead to anemia above and beyond loss of quality of life. Efforts to manage such heavy bleeding with larger and larger amounts of progesterone can lead to sedation which is another quality of life issue with loss of energy.
Progestins, fake progesterone drugs, inhibit the HPOA and then progesterone production is reduced. Progesterone is cardio protective and this is where warning re blood clots, heart attacks and strokes comes from. Pharmaceutical HRT has these problems. A women could use those products as they are cost and dose efficient and also use some real progesterone cream and reduce risks. In men, testosterone balances estrogens as progesterone does in women.
Women really have a lot of difficulties.