It's about the decline in heart function as we age and a possible cause. It seems that with some of the stuff they're coming out with, combining three or four treatments could potentially add 20-40 years to your life, which of course wouldn't necessarily be a good thing to have people around that long, as we already have to many people.
ye and add to that the fact that although your heart may function that much longer your bowels probably wont, wow an extra 20-40 of shitting in your pants, no thanks
So they'll block this interesting heart protein in humans only to find the hard way that it exists for a reason, and that inhibiting it fucks something else up in raging biochemical cascade that is the human body. No thanks. Life your life, stay healthy as long as you can, and go when it is your time.