I am thinking that perhaps most guys think this problem is too small to worry about, or maybe it's just easier not to think about it at all because after all, what can one do? Looking at it from a purely numbers point-of-view can put it into perspective. The only estimate I have seen of proposed prion infection in humans comes from Great Britain where it is estimated at 100 in 1,000,000 or 1 in 10,000. It might be safe to assume that Great Britain has the highest human infection of a prion based disease (variant Creutzfeldt-Jacob Disease that is thought to have come from GB's Mad Cow epidemic), but we really don't know the numbers for prion disease anywhere else in the world. Now lets compare that to HIV infection in the U.S. which is estimated at 1.2 million out of 310 million or 1 out of 258. That would mean that prion infection in Great Britain is about 40 times less prevalent than HIV infection in the U.S. Is this a number worth gambling with? Most people now are educated enough to practice safe sex to protect themselves against STD's including HIV. Is something 40 times less prevalent small enough to ignore?
If one injected UhCG every other day for 54 years and 277 days (10,000 injections) then he essentially has a 1:1 chance of injecting prion disease at the Great Britain rate of infection. If one injects UhCG every other day for 27 years and 139 days then one has a 1:2 chance of infecting one's self. And these numbers assume that when one injects he is only injecting from a single donor each time, which we know cannot be the case.
So to be more accurate lets consider the following. I am unaware of how many donor women it takes to fill a 5000 IU vial, but for ease of calculation lets say 100 (at 50 IU per woman). The reality is that each 5000 IU vial will last (with avg inj of 250 IU) 40 days and so one will be injecting the same 100 female donors' hCG over 40 days, 20 times. Over 10,000 injections or 54 years 277 days one will be injecting the contents of 500 5000 IU vials which adds up to 50,000 women donors over that period of time. At 5,000 injections over 27 years 139 days we have 250 5000 IU vials and 25,000 donor women. These numbers mean that in order to be exposed to only 10,000 donor women equalling the 1:10,000 chance of exposure in Great Britain, it would only take a guy 2,000 injections or just under 11 years to be exposed! A 1:2 chance of exposure would occur in just under 5 and 1/2 years! These are terrible odds to play with.
If you are buying American UhCG are you safer? Well Mad Cow Disease (the suspected source of prion disease in humans vCJD) was not nearly as rampant here as it was in Great Britain, but we do have prion disease in North America besides Mad Cow. I live in an area where prion disease is thriving in the forests around me. It's called chronic wasting disease and it thrives in ungulates like white tailed deer. Just over a week ago the gun harvest of white tailed deer in WI was estimated at 236,260. Now any deer "that appear" to be infected are supposed to be detroyed, but how many infected deer that do not appear to have the disease are being consumed by families and distributed by food pantries around the state? No way to know. Prion disease can sit dormant for years, even decades within animals and humans. Where else in the world is wild game a vector for prion disease in humans? What are Indian women eating? Do we know?