T Nation

Greatest Study Ever

Valid Reason for Oral Sex

Correlation between oral sex and a low incidence of preeclampsia: a role for soluble HLA in seminal fluid?Koelman CA, Coumans AB, Nijman HW, Doxiadis II, Dekker GA, Claas FH.
Department of Immunohematology and Blood Bank, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands.

The involvement of immune mechanisms in the aetiology of preeclampsia is often suggested. Normal pregnancy is thought to be associated with a state of tolerance to the foreign antigens of the fetus, whereas in preeclamptic women this immunological tolerance might be hampered. The present study shows that oral sex and swallowing sperm is correlated with a diminished occurrence of preeclampsia which fits in the existing idea that a paternal factor is involved in the occurrence of preeclampsia. Because pregnancy has many similarities with transplantation, we hypothesize that induction of allogeneic tolerance to the paternal HLA molecules of the fetus may be crucial.

Recent data suggest that exposure, and especially oral exposure to soluble HLA (sHLA) or HLA derived peptides can lead to transplantation tolerance. Similarly, sHLA antigens, that are present in the seminal plasma, might cause tolerance in the mother to paternal antigens. In order to test whether this indeed may be the case, we investigated whether sHLA antigens are present in seminal plasma.

Using a specific ELISA we detected sHLA class I molecules in seminal plasma. The level varied between individuals and was related to the level in plasma. Further studies showed that these sHLA class I molecules included classical HLA class I alleles, such as sHLA-A2, -B7, -B51, -B35 and sHLA-A9. Preliminary data show lower levels of sHLA in seminal plasma in the preeclampsia group, although not significantly different from the control group. An extension of the present study is necessary to verify this hypothesis.

PMID: 10706945 [PubMed - indexed for MEDLINE]

another urban myth?

[quote]pointman wrote:
another urban myth?[/quote]

No. Which is why this is an excerpt from a scientific paper. Aka. they did the experiment, crunched the data and then wrote this paper explaining their findings.

Best study ever.

i actually saw a study like this referenced in an article in Mens health five or six years back. Apparantly has some legitimacy

Why haven’t I seen this on the nightly news yet? Isn’t society interested in protecting the children?

It was on CNN
There is a thread somewhere on T-Nation about it
THe link to the cnn report is now broken unfortunatly

[quote]brucevangeorge wrote:
pointman wrote:
another urban myth?

No. Which is why this is an excerpt from a scientific paper. Aka. they did the experiment, crunched the data and then wrote this paper explaining their findings.

Best study ever.[/quote]

[quote]Noodle_Arms wrote:


[/quote]
The Snopes article was a hoax. The study cited by the OP appears genuine.

Time to get our hopes up everybody!

can somebody summarize what this study says? I am not up on my biology anymore.

[quote]dblock wrote:
can somebody summarize what this study says? I am not up on my biology anymore.[/quote]

From what I understand, it is suggesting that women who swallow our little swimmers will develop a tolerance to certain dangerous pathogens during pregnancy. But I’m not a biologist either, so don’t take my word for it.

Correlation does not equal causation… remember that boys.

[quote]ShaneM686 wrote:
Correlation does not equal causation… remember that boys.[/quote]

Traitor.