overmedicated on T4 only thyroid meds means excess T4.
Excess T4 means excess Reverse T3
Excess RT3 blocks all of your Free T3 from working which means you are only getting a tiny portion of the benefit (if any) of your treatment plan.
have you ever read stopthethyroidmadness.com/things-we-have-learned or stopthethyroidmadness.com/t4-only-meds-dont-work/ ?
If not, PLEASE do so.
My wife was able to control half of her hormonal issues/symptoms (such as crippling pain from endometriosis, severe moods swings, always freezing, can't lose weight, always tired, etc.) simply by getting on the correct thyroid medication. The other half were controlled by taking progesterone.
T3 uptake is an old style test. You get better more useful information from Free T4 vs Free T3 along with Reverse T3 + 8am cortisol + ferritin/total iron capacity.
Did the doctor only run Total Estrogen?
No values for Estradiol, Estrone, or Estriol? - what about progesterone, pregnenolone, DHEA-S, D25-OH, B12, etc? If no other tests were done, please run as fast as you can away from this doctor.... only using total estrogen and using T3 uptake are major warning signs that this doc is out of his or her league when it comes to hormonal issues.
You would have better luck calling around to a compounding pharmacy and asking for a referral to an open minded HRT womens doc.