T Nation

Glucosamine Timing & Insulin

 I know that glucosamine can exert a negative effect on insulin sensitivity.  Therefore, I am curious when it should be consumed to mitigate such an effect. Should it be avoided post-workout and/or post-post-workout? Thanks.

i just take 1 serve with brekky & 1 serve with my last meal…

There is way more evidence that caffeine is worse than glucosamine wrt insulin sensitivity. But unless you’re regularly eating Ho-Hos, I personally don’t think either are a problem. If you are really worried about it, just take it at night with your (mostly) carb-free meal of cottage cheese and fish oil.

[quote]squat junky wrote:
I know that glucosamine can exert a negative effect on insulin sensitivity.[/quote]

There are conflicting reports on this (see references below).

Fortunately for us, training improves muscle insulin sensitivity for more than 24 hours (there is no “window”), which could largely mitigate any potential negative effects.

There’s no reason to avoid glucosamine in the para-workout period.

Muniyappa R et al., 2006
Pham T et al., 2007.