The saturation talk doesnt refer to the appetite boosting effect. I think datbtru talked about that. IIRC using more than the amount needed for saturation (according to bodyweight) is just extra that doesnt cause a greater GH release than the amount needed to reach the saturation point.
More = more when it comes to appetite boost. Until it becomes intolerable.
I plan to play around with 100mcg x 2 per day. But I dont weigh as much as lot of the bigger guys using this stuff.
And for the OP. No idea about IM vs SubQ but all the smart guys I know shoot it subq.