I prefer dandelion root extract because as a person with diabetes where potassium is a problem requiring supplementation, I can’t afford to have low potassium levels because it effects diabetes management.
No side effects either and it’s not a drug. As far as being as effective as prescription diuretics, I can say that it’s equal to or better.
Any diuretic that spares potassium (Spironolactone) blocks the effects of androgens affects at the receptors.
That’s the reason my endocrinologist never recommended it.
TRT can affect sodium reabsorption via the kidneys, so it may not be the estrogen causing your issues. It might be that your T dose is excessive.
It can be androgen mediated increase in 20-HETE production and subsequent dysregulation of RAAS, interaction with various mineralcorticoid conversion pathways.
Or it could be estrogen… what is your E? I used to discount estrogen as being culpable as I thought the body would naturally find homeostasis. However I’ve found if I use “trt+” as in 125mg/wk or above my estrogen catapults into supratherapeutic concentrations whereas my testosterone doesn’t necessarily correlate aside from perhaps at the peak
Testosterone IM 1x/wk doesn’t mimic homeostatic mechanisms to begin with (circadian rhythm and the likes Iikes). Various parameters… genetics, adipose tissue distribution and the likes can impact E2 conversion. Some convert more than others
I keep my T dose at 125mg or below per week otherwise I start to look like a water buffalo. How do I know it’s the E2? Well a dieuretic will knock out the water retention… but as will a dose of anastrazole… almost overnight
However I don’t take aromatase inhibitors… it’s TRT, not a cycle.
From my perspective if I’m getting E2 mediated water retention and fat gain (another side I tend to get)… the dose is simply too high. So 100-125mg is my max, with 100mg/wk being my golden standard.
75-80mg/wk works… but it’s not as good as 100mg/wk. Contrary to what others have said… I feel better with a cavg of 6-700 ng/dl as opposed to 4-500ng/dl… and I feel on top of the world with a cavg of 8-900ng/dl