T Nation

Genetic Insulin Resistance


#1

Hello I’m had an old account on here a few years ago and found the information useful, thanks in advance to any info given.

I’ve been trying to loose weight for about 6 years and I’ve spent a lot of money on personal trainers and diets followed everything to the letter but I never really had much success, gave up put all the weight back on and then 6 months later restart the process.

After dropping weight last year I have just gone through the above process and I am dieting and exercising again. I saw my fathers doctor after he asked to see myself and my sister and he ran some tests and we have all have a high genetic resistance to insulin I think he said 4-5 times higher than normal.

He has prescribed some medication and told me it should fix my weight problems and there is a chance the meds may fix the problem with in 6 months but may take longer.

Has any one heard of anything like this before?


#2

Well there is definitely a genetic component to it… whether that means you simply have bad genes for insulin sensitivity or perhaps your parents fed you a lot of crap growing up (me), it can definitely affect gene expression later on.

I’m curious as to what test he ran. Was it a blood test?

What medication? Metformin? Because that is actually quite effective. Bring up berberine with your doctor as well.


#3

Yes has has given me Metformin, is the doctor correct is saying insulin is why i put weight on so quickly. I dont eat a lot of junk food or processed foods 90 percent of the time I eat paleo as junk food and processed foods and wheat make me unwell.

I’ll chat to him about berberine next week, what is it?