This sure opened my eyes. This dude (Dr. Johnson) knows his shit about sugar.
In this video series, Dr. Richard Johnson and Dr. Joseph Mercola discuss ties between fructose and uric acid (VERY INTERESTING) and how they relate to metabolic effects such as kidney disease, diabetes, high blood pressure, fatty liver, etc etc.
"Fructose is the #1 risk factor for obesity" Dr. Johnson (You've really got to listen to the video to appreciate this comment)
(@6:00 differences between HFCS and Table sugar discussed) (@6:00-8:00 - Fatty liver from HFCS due to speed of fructose absorption) (@8:00-9:00 it's the major cause of fatty liver disease)
(@~0:45 - clinical studies in humans validating what we've seen (in rats)) (@2:00-3:00 - Dr. Johnson suggests a sugar tax and poses a strong argument, and also suggests a warning label for sugar containing foods!)
(@~2:35 - "If you take two animals and you feed one fructose, and you feed the other one the exact same number of calories, but given as dextrose or glucose, it's only the fructose fed animal that will develop obesity, insulin resistance, fatty liver, high triglycerides, signs of inflammation, vascular disease, and high blood pressure." ~Dr. Richard Johnson
...Could this be true!?!?
...He says he just completed a clinical trial that confirms this. Drugs are more effective at reducing uric acid, but sugar reduction is critical as well.)
(@3:10 - Discussion of removing fructose from GRAS list -- sugar should not be banned, but we should educate the ppl as to why restriction is necessary) (@6:40 - as fruit ripens it will be higher in fructose and lower in antioxidants, animals use this technique to get fat for the winter, the loss of vit C in fruit probably has evolutionary ties) (@7:30 - 25-30 grams of fructose per day is the recommended amount, but the less the better for sugar as a whole) (8:30-9:00 - fructose causes insulin resistance - for the same level of blood glucose, you have a higher insulin level; "YOUR TISSUE BECOME RESISTANT TO INSULIN!!!"; new data that fructose injures the pancreas itself; ...plays a role insulin resistance and eventually diabetes) (@9:10-9:27 - "Interestingly, when you eat glucose, you stimulate insulin levels, but we don't necessarily think that's bad because... insulin has a purpose ant that's to help move the glucose into the cell; You're not actually inducing insulin resistance with glucose)
(@1:00 - It can be reversed) (@~2:30 - glucose accelerates fructose absorption!) (@~2:58 - Individual differences in fructose absorption; "the transporter that takes on fructose is turned on by fructose!!!") (@4:55- PPL get more and more sensitive to sugar the older they get - will be submitting a paper on this shortly) (@ 5:50 - 9:04 - "Fructose is the #1 risk factor for obesity"...and other foods that increase uric acid have a synergistic role... and guess what the #1 food is.... hold your hats and don't shoot the messenger.... it's beer! FML! Beer belly = metabolic syndrome! -- This is Dr. Johnson's observation, but the uric acid story remains a very controversial story, but a lot of scientists are starting to realize it could be the case, and a lot pilot studies are now in the works to give credence to this))
(0:00-0:45 - the PHDs are still debating the science, ...no big news here) (@~1:40-2:20 "The purpose of the content (of the website) is that as a physician, I realized that, many years ago, that there's this lag time between the time that something is clinically appreciated by really amazing hard working researchers and scientists who understand how profoundly important concept, and that concept may take 10, 20, 30, 40 years before it's widely adopted and accepted."