The body building community rarely does any lab work and does not understand what has been learned in the TRT realm. It is typical to see a BB guy brag about how much gear he will be taking and might use anastrozole if he gets any sides [itchy nipples or gyno].
We know from TRT that if you double your T dose you are probably going to need to double your anastrozole dose. A for 500mg/week T, I do not know where the 1mg anastrozole per 100mg T starts to become non-linear. If BB guys did labs we would know more. They are often taking many different T esters as well as fake testosterones, so its always apples and oranges.
Yes, 1mg/week is a good starting point with 100mg T per week. Then labs are used to calculate dose corrections to get nearer to E2=22pg/ml
When you start TRT, if you are an anastrozole over-responder, not rare, you will crash E2 and feel like crap, impacts energy, joins, mood and libido. The effect is quite rapid. If affected, stop anastrozole for 5-6 days to wash out, ~two half-lives, and resume at 1/4th the dose. No way to know in advance, few doctors will know this.