I went off HRT and tried a restart that I ended on 11/17. During the restart the clomid seemed to work better for me than T/AI/HCG ever did. Which makes me think I was secondary. My T levels on T/AI/HCG never got very high and fluctuated month to month. It seemed like I always over responded to the AI and was bottoming out. Not to mention my HCT was always (and still is) near or over 50%. The dilemma I am faced with is 5 months post restart, T levels keep trending down. I have considered going on clomid but there are no studies on long term use plus the likely increase in E2 which can’t be managed if it is occuring in the testes. I also have a history of floaters which doesn’t help. I could go back on T/AI/HCG and do frequent blood donation/therapeutic blood letting and hopefully the second go around have more success and even keel. Or stay as is and live with what my 46 year old body is telling me. If anyone has done long term clomid, I would love to hear the ups and downs with it and any sides experienced. Also what dose. I was planning 12.5 or 25 mg EOD to try and keep E2 in respectable range. KS man if you can look at my labs for past 4 months and affirm my assessment is correct. I will also post a history of my TSH and T3/T4 as it has fluctuated. Also to be noted is my prolactin was elevated and cortisol near upper limits but have had ALOT of stress lately which could be a factor all around. Thanks.
12/4/17 1/4/18 3/6/18 4/11/18
Testosterone
193 - 824 ng/d 461 272 272 255
Testosterone Free
41.7 - 180.2 pg/mL 153.4 103.0 108.3 84.6
Prolactin
4.0 - 15.2 ng/mL 26.8 H
Estradiol 17B
<38 pg/mL 33 <25 <25 28
Hematocrit
39-51% 51.1 50.9 49.9 49.6
Below is history of TSH/T3/T4
2/17/14 4/20/15 4/25/17 4/11/18
TSH 4.100 1.040 1.320 2.030
0.400 - 5.500 uU/ml
Free T3 2.7 2.8 2.9
2.3-4.1pg/ml
T4 Free
0.9 - 1.7 ng/dL 1.3 1.2 1.2
Misc lab history DHEA-s Cortisol
4/25/17 4/11/18
DHEA-S
44.3 - 331.0 ug/dL 94.1 96.8
cortisol
ug/dL 16.3 20.4
Cortisol Reference Range: AM = 5.3-22.5
7/24/17 10/23/17 1/4/18 4/11/18
Vitamin D 25 Hydroxy
31.0 - 80.0 ng/mL 30.5 31.1 31.2 21.6 L
I am on prescription Vitamin D (I was not taking it past 2 months though)