this has been a “hot” topic for my lastest round of recent research…There are some real good papers out there on this issue, and of course there are a myriad of issues surrounding this very topic.
I don’t know where to begin with the information on this one, as there are so many factors that make sense once reviewed and assessed. One of the major roles being genetics in terms of the manner in which one burns out fat.
Two things I have learned thus far:
E probably plays a much smaller role in the fat situation than once thought of. If it does play a significant role, its most likely at extremes of bodyfat.
Insulin is a primarly player…the abdominal region has few insulin receptor sites, but a greater affinity for insulin’s effects than the glueto-femoral region…Ever wonder why lower ab fat is the last to go as a generality?
Leptin, which has the strongest correlation with subcutaneous body fat is a prime player…should we deplete all subcutaneous body fat, leptin would be severely comprised…as such, the resistance of some subcutaneous fat areas.
Cortisol and Insulin…they act in harmony. They are the major “fat storage” hormones…Cortisol with insulin is a real bad mix
Adrenergic receptory subtype a major player as well.
whether the fat site has direct access to the portal vein is a major player…visceral fat is metabolized through the portal vein, subcutaneous isn’t, thus visceral would come first
blood flow and innervation…no blood flow, no fat loss…speaks for itself
anyway, perhaps a further discussion of this matter is at hand. One final thing: the research is still very much undecided in this area…