Ehhh, I’d argue it does… above 130 is considered borderline, above 160 is considered high and 190 is considered “he needs a statin”… whilst @aaronca isn’t at 190, he’s close and his particle size is off, his + HDL is low,
Also, anything above 200 is considered detrimental, below 200 is preferable… though if low cholesterol is because HDL cholesterol has been crushed then its not preferable. His apolipoprotein B is quite high (one of main proteins within LDL known to induce organ damage over time), involved within healthy metabolism of lipids…
TRT isn’t going to help him (or hurt him) if the dosage isn’t too high, whilst I’m all for hormonal optimisation, the truth is going high (say in the 1000’s) for most will knock HDL by 10-15%, this isn’t what Aaronca needs… if @aaronca wishes to use AAS or engage within hormonal “optimisation” it is of my unprofessional opinion that a statin is a must… @aaronca I don’t know if this is possible, but if you can be honest with you’re doctor regarding what you wish to do, I’m almost certain (If you’re doctor believes in harm minimisation rather than “just say no”) you’ll be put on cholesterol lowering meds.
I also take red yeast rice extract btw, I don’t have familial hypercholesterolemia, I asked my mother “what is it that my grandmas husband had”, it turns out there’s a genetic mutation (that I may or may not harbour) in which the receptors towards LDL cholesterol don’t function adequately, thus even normal/slightly elevated levels of LDL will induce accelerated rates of lipid perioxidation… chances are though given that it was also accelerated with elevated LDL that I don’t have it
My lipids aren’t great because I’m always on 200-250mg weekly (HDL of 40-45 LDL of 105-115)
Regarding hypercholesterolemia, there were initial studies in which AAS like oxandrolone were used too “lower total cholesterol”… this was before we realised the reason total numbers were being lowered was because HDL was being crushed lol