Evolving with TRT, Evaluating Adjustments to Endocrine System; Estradiol, HCG, Supplements?

Many do not do well injecting once a week, T spikes, T–>E2 spikes, T levels drop into a cesspool of estrogen dominance. Your body fat is making that worse.

#22 needles is insane

  • self-inject 50mg T twice a week, subq, not IM, #29 1/2" 0.5ml insulin syringes, so to load, injection time is OK
  • 0.5mg anastrozole at time of injections
  • Option: 250iu hCG subq EOD to preserve testes

Target is E2=22pg/ml. With AI as above, you should feel if things are right and E2 lab can be done in 10 days to see where you are. More reading is needed for you to grasp the variables.

With your weight, your thyroid function may be low. Please see “oral body temperatures” further down.

Most MD’s get most of TRT wrong and your doc may be lacking.


Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.

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