I was reading some blogs and books on alcohol consumption and longevity/insulin sensitivity, and the topic of protein synthesis came up. The author mentioned how this is unsubstantiated in the scientific literature outside of chronic alcoholics.
I warmed up Pubmed and have been looking for 20 minutes or so (not too long), I have found a few studies in which alcohol suppressed protein synthesis chronically in alcohol abuse, but none that would correlate to social drinking (even up to 10 beers in a single sitting).
The author also pointed that testosterone reductions in men after alcohol ingestion, although present, are fairly negligible. The first study linked showed 23% decreased test are 1.5g ethanol/lb body weight for 10-16 hours; the second study was 30-40g ethanol (3 drinks?) a day for 6 weeks and noted a 6.8% decrease.
Which is not that significant unless you need that single pound of muscle over the course of 2 years (My conjecture).
So I guess my point is, does anybody know of any research that is applicable to social drinking and shows significantly negative effects on body composition.
Hell, I even saw some research to indicate that alcohol may increase insulin sensitivity chronically via increased AMPK, and there is a correlation with social drinking (7 drinks/week-ish) and lower body fat, although the mechanism is not clear.