I’m searching here about very high estradiol topics in hope I find someone with similar problem as mine is but estradiol level of those guys is nowhere near mine.
I did my blood work before cycle and estradiol was 70 pmol/L = 19 pg/mL.
Range 40 - 161 pmol/L = 10.9 - 43.86 pg/mL.
I’ve lost a libido for a day so I did blood work in 5th week and my estradiol was 2184 pmol/L (=595 pg/mL).
(Prolactin and cortisol in upper normal range, SHBG in middle normal range)
I immediately started taking Anastrozole (=Arimidex) 1mg in morning and 1mg in evening and did blood work next week.
Estradiol dropped to 1413 pmol/L (=385 pg/mL).
I didn’t change anything and I hoped it’s gonna be dropping.
Now (8th week in cycle) my estradiol is 1548 pmol/L (422 pg/mL). Still Anastrozole 1mg in morning and 1mg in evening.
Though estradiol is extremely high, I’m doing good. No bad sites but I think I would be doing better if estradiol was in range. Libido is normal.
Anastrozole only blocks the enzyme responsible for converting T to E2.
Is there a way to directly lower estradiol?