Most guys need some anastrozole. A few, not rare, are anastrozole over-responders who need 1/4th the amount that others need. Because you are struggling, you could try 1/4 mg anastrozole twice per week.
Your E2 without anastrozole would typically be of little value. While rarely some do not need anastrozole to get good libido and sexual performance, most do. Your valid, in reportable range, lab results can be used to calculate a dose to get near E2=22pg/ml.
Most need ~1mg anastrozole for every 100mg injected T ester.
T–>E2 rate is driven by FT or Bio-T levels and anastrozole needs to match T levels.
We need your labs with ranges:
TT
FT
E2
AST/ALT
CBC
hematocrit
Your body weight and fat levels can easily be affected by thyroid status and iodine intake.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.
KSman is simply a regular member on this site. Nothing more other than highly active.
I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.
The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.