I watched this video on MPMD yesterday. Thought it was a pretty good analysis of EQ and conversion to estrogen. A few points that stuck out to me.
The reported 50% conversion rate that so often gets thrown out seems to come from a study that used the Roche estrogen test that is not very accurate, and IIRC measures E1, E2, and E3, not just E2. Additionally, it was done with rabbits, not humans.
In an anecdotal report with high test and high EQ cycle blood work, E2 was crushed, but E1 was also measured, and was way higher than the high end of the range.
In the video, Derek made a guess to what actually is going on. His guess is just that, a guess after looking at data. I thought if was a reasonable guess though. He suggests that EQ is not an AI, but competes for aromatase with test. However, it is far better at binding, and shuts out all the test from converting into E2. He suggests that the EQ is converting into E1.
What are your guys thoughts on this? This is a question I have had for some time, but haven’t gotten answers that satisfy me.