Indeed an interesting topic. And something I've run into lately.
If you look at the scatter plot at that link, those of us with super-high immunoassay results are outliers. Probably most people don't need to worry too much.
My understanding is, there are three techniques for measuring estradiol: RIA, ECLIA, and LC-MS (radioimmunoassay, electrochemiluminescence immunoassay, liquid chromatography–mass spectrometry).
It's well-known that tren inflates ECLIA results (in fact, apparently some guys use it to see if their stuff's legit).
Personally, I've been relying on ECLIA from Labcorp. But since I started taking clomid, my levels have skyrocketed to over 150. The same week I had Quest 4321 done, which I believe is RIA. This reported a level well within range, in the 20s.
I can find no evidence or anecdotes about clomid affecting ECLIA.
So seems like I oughta be a case study. Trying to google this stuff basically just brings up case studies. Here's one.
And another link.
I'm waiting on LC-MS and CRP results, and considering testing immunoglobulins.